Human chorionic gonadotropin (hCG, total hCG, hCG, Total hCG, Total beta hCG) is a hormone produced by the placenta during pregnancy. Chorionic gonadotropin is a glycoprotein and consists of two subunits alpha and beta. The alpha subunits are homologous to those of the luteinizing, follicle-stimulating, and thyroid-stimulating hormones, while the beta subunits differ and provide biological and immunological specificity. The beta subunit of hCG and the beta subunit of LH have several common peptide sequences, however, the structures of the carboxyl end are individual between them. PURCHASE PEPTIDES HCG HERE
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After the fertilized egg is implanted into the wall of the uterus, the placental trophoblasts begin to synthesize hCG. The active secretion of hCG maintains the corpus luteum, which remains functionally active throughout pregnancy, and produces high concentrations of progesterone that are physiologically impossible in a non-pregnant body. A week after fertilization, the analysis of hCG during pregnancy (normal course) can show a concentration in the blood test for hCG of 50 IU / l. During the first six weeks, if you donate blood for hCG, then you can see the dynamics because the level doubles every 1.5–3 days and continues to increase until the beginning of the second trimester, after which it gradually decreases to lower values during the remainder of the pregnancy. The concentration of hCG after childbirth in the blood test for hCG is 5 IU / L.
HCG Peptide Benefits
HCG is an excellent marker that helps to identify urgent pregnancy. In healthy non-pregnant women, the concentration of the hormone in the blood test for hCG ranges from 5.3 IU / L to undetectable. In the analysis of hCG during pregnancy, its concentration increases as described above. Then there is a gradual decrease after the first trimester. An unusually low or rapidly decreasing concentration in the analysis of hCG during pregnancy may indicate pathological conditions such as an ectopic pregnancy or the threat of termination of pregnancy.
The sensitivity of the method (blood for hCG) makes it possible to diagnose pregnancy as early as the second day after a delay in menstruation. But, due to individual differences in the rate of its synthesis, it is better to donate blood for hCG. Accordingly, the conduct from a study suggests no earlier than a 3 to 5-day delay in order to avoid false-negative results. In case of doubtful results, blood for hCG should be donated twice with an interval of 2 to 3 days. When determining the removal of an ectopic pregnancy or abortion, you need to donate blood for hCG no earlier than 1 – 2 days after the operation.
According to the Order of the Ministry of Health of the American Federation of August 30, 2012, No. 107n, during embryo transfer, pregnancy diagnosis by conducting a study of the level of chorionic gonadotropin in the blood or urine is carried out 12-14 days after the embryo transfer. Ultrasound diagnostics of pregnancy is carried out from 21 days after the transfer.