HGH peptides are being researched to help numerous health problems associated with age. Here we cover some facts about HGH peptides and what the best HGH peptides are!
What is Growth Hormone?
Growth hormone is a peptide hormone made up of a total of 191 amino acids. It is produced in large quantities in the pituitary gland and then released into the blood. HGH reaches the various cells of the body via the bloodstream, where it can exert its effects. The fact that it is produced in large quantities in the pituitary gland led to the fact that HGH was previously isolated from the pituitary glands of the dead for therapeutic use.
In recent years, there has also been a reference to the danger that corresponding HGH products from the former Soviet Union are circulating on the black market. Attention is drawn to a possible risk of infection through contamination of the products.
Nowadays, technical production is guaranteed by genetic engineering using bacterial cells such as Escherichia Coli. Genetic production ensures the health safety of the products (no bacterial contamination) but also the economic supply of the hormone in large quantities.
How do HGH Peptides Work?
HGH works directly or via so-called somatomedins (IGF-1 and IGF-2, IGF = insulin-like growth factor), which are formed in the liver. In adipose tissue, it stimulates the breakdown of fats (lipolysis), while in carbohydrate metabolism it leads to an increased release of glucose from glycogen (hyperglycemia).
The degrading effect on adipose tissue makes this compound particularly interesting for sports such as bodybuilding. On the other hand, all anabolic effects such as stimulation of protein synthesis to improve muscle growth and stimulation of skeletal growth are largely achieved indirectly via IGF-1.
For the therapeutic use of HGH, there are currently only two main clinical pictures in question: dwarfism in children and HGH deficiency in adults.
Growth Hormone Deficiency in Adults
Growth hormone in adults is important for the metabolism of lipids and carbohydrates. It is essential for the normal functioning of the body in fasting states and has a predominant role in energy balance. GH deficiency in adults is associated with metabolic problems, such as increased body fat, altered lipid profiles in the blood, decreased exercise capacity, bone mineral density, and insulin sensitivity.
The causes of growth hormone deficiency are an expanding mass in the sella turcica that compresses somatotropic function, damage to the hypothalamic-pituitary neuroendocrine pathways, or local vascular compromise produced by surgery, radiation therapy, or head trauma.
Does HGH peptides dosage work?
An accurate biochemical diagnosis is necessary to confirm acquired growth hormone deficiency, which is associated with central obesity, loss of lean muscle mass, decreased bone mass, and variable effect on the quality of life.
The often nonspecific features of growth hormone deficiency in adults can be reversed or improved with sustained daily hormone replacement therapy.
HGH peptides studies
There is no robust evidence that giving growth hormone to non-deficient patients is helpful for other purposes, such as aging and improved athletic performance. Hormones are chemical signals that exert their action on organs and tissues located far from the place where they have been synthesized. Many hormones have a peptide structure, such as:
Oxytocin
Nonapeptide (CYIQNCPLG) is secreted by the pituitary. It causes uterine contraction and the secretion of milk by the mammary gland, facilitating the delivery and feeding of the newborn.
Vasopressin: nonapeptide (CYFQNCPRG) that induces water reabsorption in the kidney (also called antidiuretic hormone).
Somatostatin
Tetradecapeptide inhibits growth hormone release.
Insulin
The hormone is composed of 51 AA synthesized in the pancreas. It stimulates the absorption of glucose by the cells. Its absence is a cause of diabetes. Insulin was the first peptide to be chemically sequenced. For this work, Frederick Sanger received the Nobel Prize in Chemistry in 1958. It is made up of two polypeptide chains linked together by three disulfide bridges (in yellow in the figure in the table below)
Glucagon/GLP-1
Hormones composed of 29 AA are released by the pancreas when blood sugar levels are high. It causes glycogen to hydrolyze in the liver to generate glucose. Its effects are the opposite of those of insulin.
Where to buy HGH Peptides?
If you are in the research industry make sure you buy from a reputable source. We can recommend Peptide Sciences for buying HGH peptides!