Tirzepatide for sale, the anti-obesity drug that achieves weight loss similar to surgery.
The scientific community analyzes the new treatment capable of reducing weight by an average of 21% and which has not yet been subjected to peer review.
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18% of the United States population compared to 23% at European level suffers from obesity , a chronic disease, according to the WHO , whose consequences for health are known as an increased risk of suffering from diabetes, coronary or neurodegenerative diseases and hypertension. The scientific community has been searching for an effective anti-obesity drug for some time and is now analyzing the finding published in The New England Journal of Medicine .
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So What Works?
It is called Tirzepatide for sale and it is an injection that you have to take every week. Up to 15 milligrams are injected. According to the data provided by the researchers, over 72 weeks an average weight loss of 21% can be achieved, the equivalent of lowering the average weight of the participants from 104 to 82 kilos. In addition, 91% of the participants lost more than 5% of their weight: 83% lost more than 10%; and 57%, more than 20%. Therefore, they managed to considerably reduce their body mass index.
The multinational responsible is Eli Lilly , to whom the data on its effectiveness belongs. The research has not yet been peer-reviewed by obesity experts.
How does tirzepatide work?
Tirzepatide acts in a double action against obesity. On the one hand, it activates the GLP-1 peptide that reduces the sensation of appetite. This is something that other treatments already did. On the other hand, it activates the peptide GIP which is believed to regulate the accumulation of fat in the body.
One of the questions that arise has to do with the duration of treatment. For now, it is believed that the treatment can be administered for a year until weight loss stabilizes and then withdraw it with the aim of maintaining it.
What are the drawbacks of tirzepatide?
In the treatment with tirzepatide, side effects have been seen to be mostly mild and transient. The most common have been nausea, which affected 31% and diarrhea in 23%. From then on, and as it is a new drug, the consequences it may have in the long term are unknown.
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Another aspect to take into account has to do with the economic cost. That is, with the price at which it can go on sale. There are no estimates yet and we can only be guided by a similar drug that is already on the market. Semaglutide, from the company Novo Nordisk, costs $1,300 a month.
When can it go on sale?
2,539 volunteers have participated in the clinical trial that is now in phase 3, the last stage before sending the conclusions to the drug agencies for authorization. Keep in mind that tirzepatide is already approved in Europe and the US for the treatment of type 2 diabetes.
Regarding the characteristics of the participants, 67% were women with an average age of 45 years and an average weight of 104 kilos. The study included people who were moderately overweight, with a body mass index of less than 30, to people who were morbidly obese; that is, with a BMI greater than 40.
44% of Americans gained weight during confinement, according to a study by the US Obesity Society. And getting rid of those extra kilos is not easy: the survey carried out by the same society concluded that 8 out of 10 people fail in their attempt to lose weight.